Comphya is a Swiss medical device company, spin-off from the Swiss Federal Institute of Technology (EPFL). Their team is developing the first implantable neurostimulator to treat erectile dysfunction in non-responders to oral drugs, such as spinal cord injury individuals. To have sexual intercourse, non-responders to oral drugs resort to intrapenial injections or penile implants, which are quite problematic and outdated. Injections are effective, however, it causes severe side effects, such as pain, discomfort, bleeding, hematoma, priapism, and penile fibrosis. A penile prosthesis is the last therapeutic option, it is an irreversible and destructive method with the risk of intra- and post-operative complications, frequently requiring surgical revision. Thus, there is a clear unmet clinical need for better modalities to treat ED.
The technology is based on neuroprosthetics principles and consists of implanting electrodes in the pelvic cavity, which will selectively activate the nerve to trigger penile erection. The device, named CaverSTIM, will provide self-controlled stimulation (via a wireless remote control) to the distal portion of the disrupted cavernous nerve to achieve and maintain a physiological penile erection for the duration of the intercourse. This envisioned medical device will improve the actual methods for the treatment of erectile dysfunction in spinal cord injury individuals, providing a safer, non-traumatic, comfortable, spontaneous and more effective alternative.
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Rodrigo Fraga, co-founder and CEO
Rodrigo is BSc in pharmacy and Ph.D. in pharmacology. He has over 10 years’ experience in the scientific space of vascular biology, sexual medicine, and male erection. In the last years, he published over 60 scientific articles in prestigious international journals. His scientific work on sexual medicine has been recognized by the International Society of Sexual Medicine with the Jean-Francois Ginestié Prize-2012. Rodrigo holds 8 inventions patented in the field of cardiovascular diseases, erectile dysfunction, and alopecia. In the last 5 years, after inventing the core technology of Comphya together with Nikos Stergiopulos, Rodrigo has gathered business skills acting on fundraising, business development, intellectual property, and the general management of the company.
Mikael Sturny, co-founder and CTO
Mike is a life science engineer and Ph.D. graduated from the Swiss Federal Institute of Technology in Lausanne (EPFL). Throughout his education and doctoral studies in biotechnology and bioengineering, he brings strong expertise in biomedical technologies and medical device development, microfabrication, prototyping, quality management as well as clinical study management.
Fiona Joseph, Director of Clinical and Regulatory Affairs
Fiona is expert in regulatory and clinical affairs. She is biomedical engineer (MSc) graduated from the EPFL. During her studies in Life Sciences engineering, she develops abilities in biomedical technologies, neuro-engineering, medical device development, and regulatory and clinical affairs.