Spinal Cord Stimulation (SCS) Clinical Trials

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| SCS Clinical Trials

Canadian Team Planning Grant

Praxis developed a Request for Applications (RFA) to increase collaboration between researchers, clinicians, consumers, and other stakeholders and between multiple study centres. The intent was to develop and submit a major grant proposal for spinal cord stimulation in SCI as well as increase high quality and robust studies for developing and evaluating spinal cord stimulation in SCI to advance the evidence for regulatory approval process.

Click here for more information on the RFA.

Grant Recipients

The projects exploring spinal cord stimulation technologies are listed below along with status updates.

Principal Investigator(s)	Project Summary	Grant Amount
Andrei Krassioukov	Collection of pilot data on the effects of transcutaneous stimulation of spinal cord in promoting recovery of bladder, bowel and sexual functions in individuals with SCI. The goal of this project is to seek additional funding for a large multi-centre study.	$50,000
	Update: With the support of this Team Planning Grant from Praxis, Dr. Krassioukov applied for major funding from the US Department of Defense Office of the Congressionally Directed Medical Research Programs (CDMRP) to conduct a translational study on spinal cord stimulation. His application was recommended for funding for the F21 Spinal Cord Injury Research Program Translational Research Award.
Marina Martinez	Development of a collaborative platform for neuroprosthetic innovation in sensorimotor rehabilitation. The goal of this project is to seek additional funding for a large multi-centre study.	$50,000
	Update: This team has applied for major funding at four funding agencies and are waiting to hear results.
Dalton Wolfe	Development of a spinal cord neuromodulation network and open-source modules and protocols. The goal of this project is to seek additional funding for a large multi-centre study.	$50,000
	Update: Currently this team is working to identify targeted funding agencies.

Scoping Review

The SCS Scoping Review is designed to describe the status of SCS research in the restoration and/or improvement of motor, sensory and autonomic function for individuals living with spinal cord injuries. There were 103 original research articles identified with the review. Analysis will highlight priority areas where more research is needed to improve the evidence for efficacy (that it works) and safety.

Status

Spinal Cord Stimulation Research in the Restoration of Motor, Sensory and Autonomic Function for Individuals Living With Spinal Cord Injuries: A Scoping Review has been published.

Clinical Trials

Interested in finding or participating in current clinical trials? Learn more at:

- SciTrials.org
- ClinicalTrials.gov

Spinal Cord Stimulation Initiatives

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